Response to Comment on "Molecular and neural basis of contagious itch behavior in mice".
نویسندگان
چکیده
Liljencrantz et al report the failure of observing contagious itch behavior using mice injected with histamine as the demonstrators. Analysis of their results shows that the histamine model is limited by inadequate frequency and duration of scratching bouts required for contagious itch test. To streamline the contagious itch test, the screen paradigm is highly recommended.
منابع مشابه
Comment on "Molecular and neural basis of contagious itch behavior in mice".
Yu et al (Reports, 10 March 2017, p. 1072) state that contagious itch occurs in mice based on imitative scratching in normal mice observing excessive scratching in genetically modified demonstrator mice. However, despite employing multiple behavioral analysis approaches, we were unable to extend these findings to normal mice observing the well-established histamine model of acute itch in demons...
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ورودعنوان ژورنال:
- Science
دوره 357 6347 شماره
صفحات -
تاریخ انتشار 2017